Qfitlia® (fitusiran) offers a tailored approach to dosing
“There’s real peace of mind knowing that we have active testing to make sure I’m on the right dose.”
— Benjamin
Moderate hemophilia A with inhibitors
Currently taking 20 mg of Qfitlia every other month
Benjamin's tailored dosing experience
Start your Qfitlia journey with confidence:
Once a baseline antithrombin test is complete, dosing is tailored using 4 antithrombin tests during the first 6 months of treatment.*
If a dose adjustment is needed, your doctor will repeat the required antithrombin testing over another 6 months. In the clinical study, 90% of people required 0-1 dose adjustment.
Once you reach the right dose for you, antithrombin testing is only needed once a year, along with periodic liver testing.
“Qfitlia feels like a great fit for my lifestyle, mainly because of the frequency of use. Now it’s every other month instead of multiple times a week.”
— Chris
Severe hemophilia A without inhibitors
Currently taking 20 mg of Qfitlia every other month
Ready to begin? Sanofi has partnered with Labcorp to help make getting started seamless.
- Sanofi partners with Labcorp to help eligible patients access certain required antithrombin and liver function tests. Ask your doctor for more information
- If you’re having difficulty accessing testing at Labcorp or your hemophilia treatment center (HTC), HemAssist™ Sanofi Support may have a program to help. Call HemAssist (1-833-723-5463) and speak to a Case Manager if you have any additional questions
- Sanofi has a mobile phlebotomy program for eligible patients to complete required testing. If you're having difficulty accessing testing at Labcorp or your hemophilia treatment center (HTC), HemAssist™ Sanofi support may help. Call HemAssist (1-833-723-5463) and speak to a Case Manager if you have any additional questions.
* The onboarding process also includes monthly LFTs for the first 6 months of treatment, or the first 6 months after a dose adjustment. After that period, liver activity is only tested annually or as needed.
† In the clinical study of 227 patients, ~67% of people with hemophilia took Qfitlia every other month, and ~19% took it monthly.
‡ Antithrombin testing restarts after any dose adjustment.
LFT=liver function test.
It is not known if Qfitlia is safe and effective in children younger than 12 years of age.
Qfitlia can cause SERIOUS SIDE EFFECTS, including:
Abnormal blood clotting (thrombotic events): Serious blood clots have occurred in people treated with Qfitlia. Qfitlia can cause blood clots to form in the blood vessels in your arms, legs, lungs, heart, brain, eyes, or head. Your risk of blood clots is greater if your antithrombin (AT) blood level is persistently less than 15% or if you have certain other conditions. Your healthcare provider (HCP) will check your AT blood levels before and during treatment with Qfitlia
Gallbladder disease: Qfitlia can cause gallstones and inflammation of your gallbladder, which might require surgery to remove your gallbladder. Tell your HCP right away if you develop stomach pain, indigestion, nausea, or vomiting. Your HCP may temporarily or permanently stop Qfitlia if you develop any of these symptoms
What is the most important information I should know about Qfitlia?
Qfitlia helps your blood form clots. Do not stop using Qfitlia without talking to your HCP. If you miss doses or stop using Qfitlia, you may no longer be protected against bleeding.
Use of a clotting factor concentrate (CFC) or bypassing agent (BPA) to help protect against bleeding must be stopped within 7 days after your first dose of Qfitlia.
Your HCP may prescribe on-demand CFC or BPA if you bleed during treatment with Qfitlia. Carefully follow your HCP’s instructions regarding when to use on-demand treatment with CFC or BPA, including the prescribed dose and timing of the CFC or BPA.
Get medical help right away if you get any of these signs or symptoms of blood clots during or after treatment with Qfitlia:
- Swelling, pain, or redness in arms or legs
- Coughing up blood
- Shortness of breath
- Severe chest pain or tightness of the chest
- Fast heart rate
- Feeling faint or passing out
- Severe or persistent headache
- Difficulty speaking or understanding language
- Feeling confused
- Numbness or weakness in your face, arms, or legs
- Sudden loss or changes in your vision, eye pain, or swelling
What are the possible side effects of Qfitlia?
Qfitlia can cause other serious side effects, including an increase in your blood liver enzymes. Your HCP will do blood tests to check your liver function before and during treatment with Qfitlia
The most common side effects of Qfitlia include viral infection, common cold symptoms, and bacterial infection
These are not all the possible side effects of Qfitlia.
What should I tell my HCP before using Qfitlia?
Tell your HCP about all of your medical conditions, including if you have liver problems, a history of gallbladder disease, are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed
Females who are able to become pregnant: Hormonal birth control may increase your risk of blood clots if used during treatment with Qfitlia. Talk to your HCP about effective forms of non-hormonal birth control you can use before starting and during treatment with Qfitlia
Tell your HCP about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements
